Prof. Pei-Wen Cheng | Medicinal Chemistry | Women Researcher Award

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Prof. Pei-Wen Cheng | Medicinal Chemistry | Women Researcher Award

Prof. Pei-Wen Cheng is a distinguished academic and researcher specializing in nanomedicine, pharmacology, and metabolic syndrome. She has built a strong career through dedicated research and teaching, advancing innovative approaches in medical sciences. Her academic journey spans several prestigious institutions in Taiwan and abroad, reflecting her global perspective and commitment to scientific excellence. With expertise rooted in natural product research, pharmacological studies, and biomedical applications, she has made significant contributions to the field. Prof. Cheng continues to drive impactful research while mentoring students and collaborating with colleagues, establishing herself as a respected figure in medical education and biomedical research.

Kaohsiung Veterans General Hospital | Taiwan

Author Profile

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Academic Journey

Prof. Pei-Wen Cheng earned her Ph.D. degree from Kaohsiung Medical University’s Graduate Institute of Natural Products. She further advanced her career through postdoctoral research at the Faculty of Medicine, Dalhousie University and later at the Department of Medical Education and Research, Kaohsiung Veterans General Hospital (Taiwan), where she deepened her expertise in medical sciences.

Professional Career

Prof. Cheng began her academic role as an Assistant Professor at National Sun Yat-sen University while also serving as an Assistant Researcher at Kaohsiung Veterans General Hospital. She then advanced to the position of Associate Professor at National Sun Yat-sen University and Associate Researcher at the hospital, where she contributed significantly to both teaching and research. She is currently a Professor at National Sun Yat-sen University, recognized for her impactful contributions to science and education.

Research Interests

Her primary research focuses on nanomedicine, pharmacology, and metabolic syndrome. Prof. Cheng’s innovative work bridges the gap between nanotechnology and biomedical applications, aiming to develop novel therapeutic strategies that improve human health and address critical challenges in modern medicine.

Notable Publications

Current mechanistic concepts in ischemia and reperfusion injury
Authors: Meng-Yu Wu, Giou-Teng Yiang, Wan-Ting Liao, Andy Po-Yi Tsai, Yeung-Leung Cheng, Pei-Wen Cheng, Chia-Ying Li, Chia-Jung Li
Journal: Cellular Physiology and Biochemistry
Year: 2018

Application of time series analysis in modelling and forecasting emergency department visits in a medical centre in Southern Taiwan
Authors: Wang-Chuan Juang, Sin-Jhih Huang, Fong-Dee Huang, Pei-Wen Cheng, Shue-Ren Wann
Journal: BMJ Open
Year: 2017

Resveratrol decreases fructose‐induced oxidative stress, mediated by NADPH oxidase via an AMPK‐dependent mechanism
Authors: Pei‐Wen Cheng, Wen‐Yu Ho, Yu‐Ting Su, Pei‐Jung Lu, Bo‐Zone Chen, Wen‐Han Cheng, Wen‐Hsien Lu, Gwo‐Ching Sun, Tung‐Chen Yeh, Michael Hsiao, Ching‐Jiunn Tseng
Journal: British Journal of Pharmacology
Year: 2014

Angiotensin II inhibits neuronal nitric oxide synthase activation through the ERK1/2-RSK signaling pathway to modulate central control of blood pressure
Authors: Wen-Han Cheng, Pei-Jung Lu, Wen-Yu Ho, Che-Se Tung, Pei-Wen Cheng, Michael Hsiao, Ching-Jiunn Tseng
Journal: Circulation Research
Year: 2010

Effect of resveratrol on reactive oxygen species-induced cognitive impairment in rats with angiotensin II-induced early Alzheimer’s disease
Authors: Yu-Te Lin, Yi-Chung Wu, Gwo-Ching Sun, Chiu-Yi Ho, Tzyy-Yue Wong, Ching-Huang Lin, Hsin-Hung Chen, Tung-Chen Yeh, Chia-Jung Li, Ching-Jiunn Tseng, Pei-Wen Cheng
Journal: Journal of Clinical Medicine
Year: 2018

Caffeine intake improves fructose-induced hypertension and insulin resistance by enhancing central insulin signaling
Authors: Tung-Chen Yeh, Chun-Peng Liu, Wen-Han Cheng, Bo-Rong Chen, Pei-Jung Lu, Pei-Wen Cheng, Wen-Yu Ho, Gwo-Ching Sun, Jau-Cheng Liou, Ching-Jiunn Tseng
Journal: Hypertension
Year: 2014

Conclusion 

Prof. Pei-Wen Cheng exemplifies dedication to advancing scientific knowledge and fostering innovation in medical research. Her career journey from doctoral studies to professorship reflects her commitment to academic excellence and impactful research. With a focus on nanomedicine, pharmacology, and metabolic syndrome, she continues to push the boundaries of biomedical science. Her contributions extend beyond research, encompassing teaching, mentorship, and international collaborations that strengthen academic networks. As a professor, she remains committed to inspiring future scientists while pursuing groundbreaking discoveries. Prof. Cheng’s work demonstrates how multidisciplinary approaches can contribute to improved healthcare outcomes and scientific advancement on a global scale.

Mrs. Min Xu | Pharmaceutical Chemistry | Best Researcher Award

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Mrs. Min Xu | Pharmaceutical Chemistry | Best Researcher Award

Mrs. Min Xu | Kunming University of Science and Technology | China

Min Xu is a distinguished researcher in the field of natural product chemistry and chemical biology, serving as a professor at Kunming University of Technology and Science (KUTS) in China. She has garnered significant recognition for her interdisciplinary work in discovering active natural molecules from Southwest ethnic medicine.

Professional Profile

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🎓 Education and Academic Journey

Min Xu has pursued a commendable academic path marked by excellence and dedication. She earned her Ph.D. in Phytochemistry from the Kunming Institute of Botany, CAS, in 2007. Her undergraduate studies culminated in a Bachelor of Science in Traditional Chinese Medicine from the Yunnan College of Traditional Chinese Medicine in 1999. These academic foundations have profoundly shaped her research focus in natural product chemistry and chemical biology.

🔬 Research Major and Interests

Min Xu is a dedicated researcher specializing in natural product chemistry, seamlessly integrating it with chemical biology to address significant scientific challenges. Her work focuses on discovering and identifying active natural molecules from Southwest ethnic medicine, an area rich in medicinal biodiversity. She is deeply involved in optimizing the structure-activity relationship of these compounds for novel probe development and assembly. A key aspect of her research is the discovery of innovative leading compounds and their mechanisms of action, particularly in addressing major diseases such as tumors, infectious diseases, and aging-related disorders. This interdisciplinary approach highlights her commitment to advancing health sciences through the potential of nature-derived compounds.

🏆 Academic Honors and Achievements

Min Xu’s groundbreaking contributions have been recognized with several prestigious honors. In 2016, she was named a Young Academic Leader of Yunnan Province, a testament to her leadership in the scientific community. She was also honored by the Talents of West Light Foundation of the Chinese Academy of Sciences in 2012. Earlier in her career, she received the West China Excellent Graduate Students Prize in 2001 from CAS and the Excellent Undergraduate Students Prize in 1999 from Yunnan College of Traditional Chinese Medicine. These accolades underscore her pioneering work and academic excellence in natural product chemistry.

💼 Professional Experience

Min Xu has held various prominent roles throughout her career, contributing significantly to academia and research. Since 2016, she has been a Professor at the Kunming University of Technology and Science (KUTS), where she continues to drive innovative research. Previously, she served as an Associate Professor at the Kunming Institute of Botany (CAS) from 2011 to 2015 and as an Assistant Researcher at the State Key Laboratory of Phytochemistry and Plant Resources in West China from 2007 to 2010. Her international experience includes a position as a Research Fellow at the Eskitis Institute for Cell and Molecular Therapies, Griffith University, Australia, from 2008 to 2009. These roles have enabled her to pioneer transformative research and mentor emerging leaders in the field.

💰 Grants and Funding Awards

Min Xu has successfully secured over 20 grants, showcasing her ability to attract significant funding for impactful research. Notable awards include a 16-million RMB grant for advancing the resources of Southwest ethnic medicine and developing treatments for hepatitis B (2023–2026). She also received a 600,000 RMB grant for her work in chemical biology under the Program for Innovative Research Team in University of Yunnan Province (2019–2022). Another remarkable project involved a 4.2-million RMB grant focused on the investigation and development of aromatic plants in Yunnan (2016–2019). These successes highlight her capacity for leading transformative research initiatives and her vision for pharmaceutical advancements.

🌱 Research Contributions and Experiences

Min Xu has consistently pushed the boundaries of natural product chemistry through her extensive research experiences. Her studies have yielded key discoveries, such as the antiviral terpenes from the Euphorbiaceae family, antifungal compounds from the genus Piper, and anti-hepatitis B virus sesquiterpenoids. Her interdisciplinary methods—ranging from compound assembly to mechanism analysis—have propelled advancements in pharmaceutical sciences. These contributions underscore her significant role in bridging natural product chemistry with therapeutic innovation.

🧪 Innovative Research Interests

Min Xu’s current research focuses on the efficient discovery and identification of bioactive natural products, with a special emphasis on Southwest ethnic medicine. Her work encompasses chemical probe development and the discovery of novel treatments for major diseases such as tumors and infectious ailments. Her approach not only enhances our understanding of medicinal chemistry but also paves the way for innovative solutions to global health challenges.

Publications Top Noted📚

Ramifloraolides A − D, four highly oxygenated picrotoxane-type sesquiterpenoids from the stems of Baccaurea ramiflora and their antithrombotic activity

Authors: Li-Hua Su, Wei Wang, Ya-Lin Yang, Min-Rong Chu, Yi-Can Wang, Hao-Hao Lv, Zi-Ang Zhou, Hao Chen, Shao-Xing Dai, Min Xu

Journal: Bioorganic Chemistry

Year: 2024

Lappanolides A−N, fourteen undescribed sesquiterpenoids from Saussurea costus (Syn. Saussurea lappa) and their anti-HBV activity

Authors: Hong-Bo Li, Shi-Qun Bai, Teng-Yun Shu, Qiong Wang, Hao Chen, Li-Hua Su, Min Xu

Journal: Phytochemistry

Year: 2024

Tsaokoflavanols A1–J1: Flavanol-fatty alcohol hybrids with HPL inhibitory activity from Amomum tsao-ko

Authors: Tian-Rong Yang, Shi-Chao Huang, Yun-Fen Wang, Zai-Xiang Lou, Shao-Xing Dai, Li-Hua Su, Min Xu

Journal: Phytochemistry

Year: 2024

Essential oil of lemon myrtle (Backhousia citriodora) induces S-phase cell cycle arrest and apoptosis in HepG2 cells

Authors: Yun-Fen Wang, Yang Zheng, Yin-Yue Cha, Yang Feng, Shao-Xing Dai, Sanjun Zhao, Hao Chen, Min Xu

Journal: Journal of Ethnopharmacology

Year: 2023

Thiol–Chromene “Click” Reaction-Activated Chemiluminescent Probe for Thiol Detection In Vitro and In Vivo

Authors: Baoqu Wang, Xiaoxue Tian, Xing-Cong Li, Kui Cheng, Min Xu

Journal: ACS Applied Materials & Interfaces

Year: 2023