University of Virginia, United States
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š Educational Background
Dr. Katla completed his Ph.D. in Synthetic Organic Chemistry from the Indian Institute of Chemical Technology (IICT), Hyderabad, India, in 2014. He obtained his Masterās degree (M.Sc.) in Organic Chemistry from Osmania University in 2008 and earned his Bachelor of Science (B.Sc.) with a major in Chemistry, Physics, and Mathematics from Kakatiya University, Warangal, in 2005. His academic background has been instrumental in shaping his research focus on heterocyclic chemistry and bioactive molecule synthesis.
š§¬ Research Skills
Dr. Katla possesses strong expertise in drug-lipid conjugate development to enhance the physicochemical properties of APIs and their encapsulation into nanoparticles. He has synthesized a range of polymeric nanoparticles for delivering both hydrophobic and hydrophilic drugs, adhering to Good Laboratory Practices and chemical safety regulations. His skills include multi-step organic synthesis, solid-phase synthesis, and various modern techniques such as microwave-assisted, ultrasound-assisted, and green chemistry approaches. He is adept in metal-mediated catalytic transformations, including CāC, CāS, CāSe, CāO, CāN, and CāH bond coupling reactions using parallel synthesizers. Dr. Katla is highly proficient in NMR spectroscopy (Ā¹H, Ā¹Ā³C, DEPT, NOESY, COSY), MNova software, LC-MS, FT-IR, UV-VIS, and flash chromatography, as well as nanoparticle characterization techniques such as DLS, TEM, and X-ray diffraction.
š§āš¬ Academic and Research Experience
At the University of Virginia, since February 2023, Dr. Katla has synthesized Colchifoline-DLC from Colchicine and developed liposomal formulations to enhance drug delivery. He created Romidepsin-loaded polymeric nanoparticles (PNPs) using various amphiphilic co-block polymers and examined drug-polymer interactions via Proton-NMR. His responsibilities include designing polymeric nanoparticles, drug-fatty acid conjugation, ester bond optimization, and scale-up for pre-clinical nanoparticle formulations, along with mentoring undergraduate students.
From 2021 to 2023, as a Foreign Visiting Professor at the Federal University of Rio Grande (FURG), Brazil, he developed microwave-assisted CāS and CāSe cross-coupling reactions using eco-friendly catalysts like Pd/Rice Husk Ash and Pd/Banana Peel Ash. He was also involved in the development of small-scale bioactive molecules for conditions like Alzheimerās, HIV, and AChE inhibition, alongside exploring photo-physical properties and supervising masterās and doctoral students. Earlier, from 2018 to 2020, at the Federal University of Grande Dourados (UFGD) in Brazil, he focused on green synthetic methods including the use of zinc and cobalt catalysts for generating thia-Michael derivatives, isatin-derived N,S-acetals, and benzothiazolyl triazolium analogues. He also investigated their biological activity and DNA-binding properties, and mentored several graduate and undergraduate students.
š Industrial Experience
Between December 2017 and June 2018, Dr. Katla worked at Madin Life Sciences Pvt. Ltd., Hyderabad, as a Research Scientist, contributing to FTE projects related to the development of labeled APIs and heterocyclic intermediates, particularly imidazoles and pyrazoles for pharmaceutical applications.
š¬ Postdoctoral Research
From 2014 to 2017, Dr. Katla was a Postdoctoral Fellow at UFGD, Brazil, under Prof. Nelson Domingues. He synthesized a variety of heterocyclic scaffolds including polyfunctionalized pyrroles, benzimidazoles, quinazolinones, and trifluoromethylated spiro-compounds. His work involved CāS coupling reactions using palladium catalysts and CāH arylation using magnetically separable nano copper ferrite catalysts.
šØāš« Supervisory and Teaching Experience
Dr. Katla has co-supervised several Ph.D., Masterās, and undergraduate students across multiple Brazilian universities. He has provided extensive guidance in synthetic methodology development, literature search, spectral analysis (NMR & MS), purification techniques, and structural interpretation of novel compounds, demonstrating strong commitment to research training and mentorship.
š Honors and Awards
Dr. Katla has received multiple international recognitions. In 2023, he was selected as Research Scientist at the University of Virginia. He secured first position in Foreign Visiting Professor selections at FURG (2020), UFGD (2017), and in Biotechnology & Biodiversity (2020). He earned second position in Chemistry at the University of Brasilia (2022) and in the Graduate Program in Chemistry (2016). In 2014, he received the CNPq-BJT Level-A Young Talent Postdoctoral Fellowship in Brazil. He also holds a prestigious Junior Research Fellowship (JRF-UGC) awarded by CSIR, India in 2008.
š Certifications
To strengthen his communication and professional skills, Dr. Katla completed āLearn Business Englishā via Udemy and received a certificate in āPersonality Development and Communication Skillsā from the Centre for English Language Training (CELT), Osmania University, Hyderabad, India.
Notable Publicationsš
š Palladium Nanoparticles Dispersed in Alginate Beads as an Efficient, Ecoāfriendly, and Sustainable Heterogeneous Catalyst: Testing in CarbonāSulfur and CarbonāCarbon CrossāCoupling Reactions
Authors: Ramesh Katla, Rakhi Katla, Daniel Rapachi, Marcos A. Gelesky, JoĆ£o Henrique Z. dos Santos, Gilber R. Rosa, Clarissa H. Rosa
Journal: Asian Journal of Organic Chemistry
Year: 2025
š Pyrrolidinium Acetate (PyrrIL) as a Green and Recyclable Catalyst: Synthesis of 2-Phenyl Benzimidazoles and 2-Phenyl Benzothiazoles under Solvent-Free Conditions at Room Temperature
Authors: Ramesh Katla, Rakhi Katla
Journal: SynOpen
Year: 2023
š Pd-G3 XantPhos Mediated Approach to Bis-arylsulfenyl-benzo-2,1,3-thiadiazoles under Microwave Irradiation in DMF: Synthesis and Fluorescent Properties
Authors: Ramesh Katla, Rakhi Katla, EliƩzer Quadro Oreste, Felipe Kessler
Journal: Synthesis
Year: 2023
š XantPhos Pd-G3 as an Efficient Catalyst: Microwave-Assisted CāS Cross-Coupling Reaction in DMF
Authors: Rakhi Katla, Ramesh Katla, Nelson L. C. Domingues
Journal: Synthesis
Year: 2023
š Microwave Assisted CāS Cross-Coupling Reaction from Thiols and 2-(4-Bromo Phenyl)-Benzothiazole Employed by CuI in Acetonitrile
Authors: Ramesh Katla, Rakhi Katla
Journal: New Journal of Chemistry
Year: 2022