Dr. Shanshan Lu | Biomolecules | Best Researcher Award

Dr. Shanshan Lu | Biomolecules | Best Researcher Award

Doctorate at Dalian University of Technology, China

Professional Profile

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🎓 Academic and Professional Background

Shanshan Lu earned her degree from the Brain Science Center, Beijing Institute of Basic Medical Sciences, where she trained under the esteemed guidance of Yizheng Wang. Her work focuses on disease mechanisms related to ischemic stroke and the development of effective drug targets. Leveraging molecular docking techniques, she investigates interactions between small molecules and proteins, providing novel insights into disease progression and therapeutic strategies.

🔬Research Interests & Contributions 

Dr. Lu’s research focuses on disease mechanisms related to ischemic stroke, aiming to explore new drug targets based on the underlying pathogenesis. One of her notable contributions is in the area of molecular docking, where she works to screen and predict interactions between small molecules and proteins and investigates how signaling pathways play a role in the development of diseases.

Her work also includes groundbreaking findings related to cortisol and its effects on sonic hedgehog (Shh)/SMO-mediated proliferation of lung fibroblasts. Dr. Lu showed how cortisol competes with cholesterol to bind the cysteine-rich domain (CRD) in SMO, ultimately inhibiting Shh/SMO signaling essential for cell proliferation. Her studies on Smoa/a(L116A) mice provided key insights into lung development, revealing abnormalities such as over-proliferation of fibroblasts and a reduction in surfactant proteins.

Publications Top Noted📝

Cortisol regulates neonatal lung development via Smoothened

Authors: Shanshan Lu, Yifei Chen, Jiawen Song, Liangliang Ren, Jun Du, Donglai Shen, Jiayin Peng, Yao Yin, Xia Li, Yuqing Wang et al.

Journal: Respiratory Research

Year: 2025

PKCα phosphorylation of GLT-1 at Ser562/563 induces glutamate excitotoxicity in ischemia in mice

Authors: Yuqing Wang, Jun Du, Shanshan Lu, Xia Li, Yifei Chen, Chao Yuan, Sheng-Tao Hou, Yizheng Wang

Journal: Signal Transduction and Targeted Therapy

Year: 2022

Smoothened is a therapeutic target for reducing glutamate toxicity in ischemic stroke

Authors: Yuqing Wang, Shanshan Lu, Yifei Chen, Liang Li, Xia Li, Zhongwei Qu, Junbo Huang, Liu Fan, Chao Yuan, Nan Song et al.

Journal: Science Translational Medicine

Year: 2021

Sonic hedgehog induces GLT-1 degradation via PKC delta to suppress its transporter activities

Authors: Yuqing Wang, Shanshan Lu, Zhongwei Qu, Lin Wu, Yizheng Wang

Journal: Neuroscience

Year: 2017

Mr. Leonardo Vitorino Costa de Aquino, Biomolecules, Best Researcher Award

Mr. Leonardo Vitorino Costa de Aquino, Biomolecules, Best Researcher Award

Mr. Leonardo Vitorino Costa de Aquino, Federal Rural University of Semi-Arid, Brazil

Profiles

Scopus

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🌟Summary

Mr. Leonardo Vitorino Costa de Aquino is a dedicated researcher and academic specializing in veterinary medicine and animal reproduction biotechnology. Currently pursuing a Ph.D. at the Universidade Federal Rural do Semi-Árido (UFERSA), Leonardo has a solid foundation in animal science and biotechnology, complemented by extensive research and project participation.

🎓Education

Ph.D. in Animal Science (in progress): Universidade Federal Rural do Semi-Árido, UFERSA, Brazil. Advisor: Alexsandra Fernandes Pereira.

Master’s in Animal Science (2020-2022): Universidade Federal Rural do Semi-Árido, UFERSA, Brazil. Advisor: Alexsandra Fernandes Pereira.

Graduation in Biotechnology (2016-2019): Universidade Federal Rural do Semi-Árido, UFERSA, Brazil. Advisor: Alexsandra Fernandes Pereira.

Secondary Education (2011-2013): Escola Estadual Aida Ramalho Cortez Pereira, EEARCP, Brazil.

💼 Professional Experience

Researcher
Laboratório de Biotecnologia Animal (LBA/UFERSA) (2022 - Present)
Participation in projects focusing on in vitro fertilization for conservation of wild species and nuclear transfer techniques.

Researcher
Departamento de Ciências Animais, UFERSA (2020 - Present)
Projects on the antioxidant potential of essential oils in bovine oocyte maturation and embryo development.

Professor
UFERSA (2020 - 2021)
Taught courses in Animal Reproduction and Biotechnology.

🔬Research Interests 

Animal Reproduction
Development of in vitro fertilization techniques and somatic cell nuclear transfer.

Biotechnology
Antioxidant properties of essential oils and their application in animal reproduction.

🏆Awards and Honors 

1st Place for Best Oral Presentation
II SEMPRO BIOTEC, UFERSA (2024)

Honorable Mention for Best Poster Presentation
II SEMPRO BIOTEC, UFERSA (2024)

Honorable Mention for Best Presentation in Agrarian Sciences
XXIX Seminário de Iniciação Científica, UFERSA (2023)

2nd Place in Photography Contest
I Simpósio Potiguar em Ciência Animal, UFERSA (2023)

Honorable Mention for Best Presentation in Agrarian Sciences
XXVIII Seminário de Iniciação Científica, UFERSA (2022)

1st Place for Best Work in Swine Reproduction
XXIV Congresso Brasileiro de Reprodução Animal (2021)

1st Place for Best Presentation in Biological Sciences
XXVII Seminário de Iniciação Científica, UFERSA (2021)

3rd Place for Best Presentation in Agrarian Sciences
XXVII Seminário de Iniciação Científica, UFERSA (2021)

Best Work in Bovine Reproduction
X Congresso Norte-Nordeste de Reprodução Animal, UEMA (2020)

Best Work in Wild Animal Reproduction
X Congresso Norte-Nordeste de Reprodução Animal, UEMA (2020)

Publications📝

Cryopreservation and Passaging Optimization for Galea spixii (Wagler, 1831) Adult Skin Fibroblast Lines: A Step Forward in Species Management and Genetic Studies

Authors: Aquino, L.V.C.D., Olindo, S.L., Silva, Y.L.F.E., Silva, A.R., Pereira, A.F.

Journal: Acta Histochemica

Year: 2024

Age and Sex Effects on Histological Features and In Vitro Culturing of Antillean Manatee (Trichechus manatus manatus, Linnaeus 1758) Dermis

Authors: Moura, Y.B.F., Aquino, L.V.C., Nascimento, M.B., Luna, F.O., Pereira, A.F.

Journal: Journal of Veterinary Medicine Series C: Anatomia Histologia Embryologia

Year: 2024

L-Proline as a Cryoprotective Agent for the Preservation of Galea Spixii Skin Fibroblasts

Authors: Aquino, L.V.C., Rodrigues, L.L.V., Olindo, S.L., Moura, Y.B.F., Pereira, A.F.

Journal: Biopreservation and Biobanking

Year: 2024

Different Methods for Seminal Plasma Removal and Sperm Selection on the Quality and Fertility of Collared Peccary Sperm

Authors: Santos, M.V.O., Silva, A.M., Aquino, L.V.C., Silva, A.R., Pereira, A.F.

Journal: Animals

Year: 2023

Morphological, Ultrastructural, and Immunocytochemical Characterization and Assessment of Puma (Puma concolor Linnaeus, 1771) Cell Lines After Extended Culture and Cryopreservation

Authors: Lira, G.P.O., Borges, A.A., Nascimento, M.B., Silva, A.R., Pereira, A.F.

Journal: Biopreservation and Biobanking

Year: 2022