Dr. Shanshan Lu | Biomolecules | Best Researcher Award

Dr. Shanshan Lu | Biomolecules | Best Researcher Award

Doctorate at Dalian University of Technology, China

Professional Profile

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🎓 Academic and Professional Background

Shanshan Lu earned her degree from the Brain Science Center, Beijing Institute of Basic Medical Sciences, where she trained under the esteemed guidance of Yizheng Wang. Her work focuses on disease mechanisms related to ischemic stroke and the development of effective drug targets. Leveraging molecular docking techniques, she investigates interactions between small molecules and proteins, providing novel insights into disease progression and therapeutic strategies.

🔬Research Interests & Contributions 

Dr. Lu’s research focuses on disease mechanisms related to ischemic stroke, aiming to explore new drug targets based on the underlying pathogenesis. One of her notable contributions is in the area of molecular docking, where she works to screen and predict interactions between small molecules and proteins and investigates how signaling pathways play a role in the development of diseases.

Her work also includes groundbreaking findings related to cortisol and its effects on sonic hedgehog (Shh)/SMO-mediated proliferation of lung fibroblasts. Dr. Lu showed how cortisol competes with cholesterol to bind the cysteine-rich domain (CRD) in SMO, ultimately inhibiting Shh/SMO signaling essential for cell proliferation. Her studies on Smoa/a(L116A) mice provided key insights into lung development, revealing abnormalities such as over-proliferation of fibroblasts and a reduction in surfactant proteins.

Publications Top Noted📝

Cortisol regulates neonatal lung development via Smoothened

Authors: Shanshan Lu, Yifei Chen, Jiawen Song, Liangliang Ren, Jun Du, Donglai Shen, Jiayin Peng, Yao Yin, Xia Li, Yuqing Wang et al.

Journal: Respiratory Research

Year: 2025

PKCα phosphorylation of GLT-1 at Ser562/563 induces glutamate excitotoxicity in ischemia in mice

Authors: Yuqing Wang, Jun Du, Shanshan Lu, Xia Li, Yifei Chen, Chao Yuan, Sheng-Tao Hou, Yizheng Wang

Journal: Signal Transduction and Targeted Therapy

Year: 2022

Smoothened is a therapeutic target for reducing glutamate toxicity in ischemic stroke

Authors: Yuqing Wang, Shanshan Lu, Yifei Chen, Liang Li, Xia Li, Zhongwei Qu, Junbo Huang, Liu Fan, Chao Yuan, Nan Song et al.

Journal: Science Translational Medicine

Year: 2021

Sonic hedgehog induces GLT-1 degradation via PKC delta to suppress its transporter activities

Authors: Yuqing Wang, Shanshan Lu, Zhongwei Qu, Lin Wu, Yizheng Wang

Journal: Neuroscience

Year: 2017

Dr. Jintian He | Biomolecules | Best Researcher Award

Dr. Jintian He | Biomolecules | Best Researcher Award

Doctorate at College of life science, Hebei normal university | China

Professional Profiles

Scopus

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🎓 Educational Background

Dr. Jingtian He has a robust academic foundation that underpins her expertise in biochemistry and molecular biology. She earned her Bachelor of Science (B.S.) in Chemistry from Hebei University, Baoding, China in July 1990. Her pursuit of advanced knowledge led her to Nankai University, Tianjin, China, where she completed her Master of Science (M.S.) in Inorganic Chemistry in June 1996. Dr. He culminated her academic journey with a Ph.D. in Biochemistry and Molecular Biology from the prestigious School of Basic Medical Sciences, Fudan University, Shanghai, China, in June 2005.

🏢 Professional Role and Expertise

Currently, Dr. Jingtian He serves as an Associate Professor in the Department of Biochemistry and Molecular Biology at the College of Life Science, Hebei Normal University, located in Shijiazhuang City, Hebei Province, China. She is a distinguished academic and researcher known for her contributions to drug delivery systems and her innovative work in micro- and nano-particle formulations.

đź’ˇ Research Focus

Dr. He’s research is centered on the development of polymeric particles for sustained and mucosal drug delivery systems, contributing significantly to advancements in pharmaceutical science. Her work has provided a deeper understanding of microsphere formulations for a variety of drugs, including erythropoietin, hepatitis B surface antigen, staphylokinase mutant, triptorelin, and non-T cell binding peptides.

One of her groundbreaking discoveries demonstrated that chitosan can enhance the transepithelial transport of both peptides and microparticles, offering new possibilities for improving drug delivery and absorption. Additionally, her research highlighted that the surface modification of PLGA micro- and nano-particles with polysaccharides serves as a promising approach for the mucosal delivery of antigens, paving the way for innovative solutions in vaccine and therapeutic delivery systems.

Publications Top Noted📚 

Enhanced phagocytosis and endosomal escape of glucan-modified microparticles in antigen-presenting cells

Authors: Kang, T.; Zhang, R.; Hou, S.; He, J.

Journal: Journal of Drug Delivery Science and Technology

Year: 2024

Adjuvant effects of chimeric flagellin and chitosan/tripolyphosphate (CS/TPP) nanogel encapsulation on immune response induced by nasal vaccination of Helicobacter pylori adhesin

Authors: Zhai, X.; Yan, X.; Meng, Q.; He, J.; Wang, G.

Journal: Acta Microbiologica Sinica

Year: 2021

Chitosan-based thermosensitive hydrogel for nasal delivery of exenatide: Effect of magnesium chloride

Authors: Li, Y.; He, J.; Lyu, X.; Wang, G.; Zhao, B.

Journal: International Journal of Pharmaceutics

Year: 2018

Co-delivery of polyinosinic:polycytidylic acid and flagellin by poly(lactic-co-glycolic acid) MPs synergistically enhances immune response elicited by intranasally delivered hepatitis B surface antigen

Authors: Dai, X.; He, J.; Zhang, R.; Xiong, F.; Zhao, B.

Journal: International Journal of Nanomedicine

Year: 2017

Surface-functionalized, pH-responsive poly(lactic-co-glycolic acid)-based microparticles for intranasal vaccine delivery: Effect of surface modification with chitosan and mannan

Authors: Li, Z.; Xiong, F.; He, J.; Dai, X.; Wang, G.

Journal: European Journal of Pharmaceutics and Biopharmaceutics

Year: 2016

Dr. raksha sunhare | Biomolecules | Women Researcher Award

Dr. raksha sunhare | Biomolecules | Women Researcher Award

Doctorate at Vidya Pvt ltd | India

Dr. Raksha Sunhare is an accomplished researcher in the field of biotechnology, specializing in probiotics development, molecular biotechnology, and clinical studies. With an impressive career spanning over a decade, she has made significant contributions to the development of high cell-density probiotics, the formulation of innovative products, and the advancement of molecular research methods.

Professional Profile

Scopus

🎓 Educational Background

Dr. Raksha Sunhare possesses a strong academic foundation with advanced degrees in biotechnology, pharmacy, and business management. She earned her Doctor of Philosophy (Ph.D.) in Molecular Biotechnology from University Putra Malaysia (2009–2014), focusing on proteomics and metagenomics in complex biological systems. Her academic excellence was evident during her Master of Technology (M.Tech) in Biotechnology at Rajiv Gandhi Proudyogiki Vishwavidyalaya, India (2005–2007), where she received the prestigious University Distinction Award. She laid the groundwork for her career in pharmaceuticals and biotechnology with a Bachelor of Pharmacy (B.Pharm) from Shri Govindram Seksaria Institute of Technology and Science, India (2000–2004). To complement her scientific expertise, Dr. Sunhare pursued a Master in Business Management from Pune University (2017–2019), equipping herself with vital leadership and managerial skills to drive impactful innovations.

đź’Ľ Professional Experience

Dr. Sunhare has excelled in diverse roles, showcasing her expertise in probiotics development, market research, and product innovation. At Unique Biotech, Hyderabad (April 2021–Feb 2022), as Manager of Probiotics-New Product Development, she formulated innovative dosage forms such as sachets, stick packs, gummies, and solutions. She played a pivotal role in designing product portfolios and conducting market gap analyses, enabling the successful branding of new products. Earlier, as a Consultant-Market Research Analyst at Healthathon Tech, Pune (Oct 2018–March 2021), she conducted extensive market research, blending qualitative and quantitative analyses to develop clinical proposals, brand tracking systems, and marketing strategies.

Recently, at Vidya Probiotics, Hassan, Dr. Sunhare led end-to-end projects in probiotics development, from strain isolation to high cell-density formulation for innovative strains like Akkermansia muciniphila. Her commitment to Good Laboratory Practices (GLP) included staff training in calibration, audits, and advanced lab techniques. As a Researcher at National Chemical Laboratory, Pune (Aug 2017–Dec 2017), she conducted biochemical experiments for product advancement, focusing on microbiological safety and efficacy. Additionally, during her tenure as a Post-doctoral Researcher at University Putra Malaysia (Aug 2014–April 2015), she explored protein alterations in preterm deliveries and ectopic pregnancies using proteomic approaches while advancing microbiome and stem cell research through metagenomic analyses.

🔬 Research Contributions

Dr. Sunhare has made significant contributions to scientific research, including developing US patent technology for high-cell-density production of strains such as Akkermansia muciniphila, Bacillus clausii, and Bacillus subtilis. Her pioneering work spans proteomics, genomics, and microbial biochemical processes, leading to advancements in probiotics and biotechnology.

🏆 Awards and Recognition

Dr. Sunhare’s achievements have been widely recognized. She was a Barefoot Ultra-Runner Ambassador and podium finisher at the 24-hour Ultra Pinkathon Worldwide in March 2019. Her academic excellence was honored with prestigious fellowships, including the Malaysian Ministry of Higher Education Fellowship (2010–2013) and Special Graduate Research Fellowship (2009). She also received the University Distinction Award during her M.Tech studies in 2007 for her outstanding academic performance.

🛠️ Key Skills

Dr. Sunhare is a versatile professional with expertise spanning multiple domains. She excels in branding and product development, designing market-driven product portfolios, and implementing effective marketing strategies. Her research proficiency includes advanced techniques in proteomics, genomics, and pharmacovigilance, along with a strong command of clinical studies and data analysis. Additionally, she is skilled in process design and enhancement, innovating formulations for probiotics while troubleshooting complex equipment-related issues.

🌟 Notable Achievements

Dr. Sunhare has collaborated on multinational projects that bridge academia and industry, contributing significantly to microbiological safety assessments that enhance product quality and shelf life. She has demonstrated exceptional leadership by mentoring and training staff in advanced laboratory processes, ensuring high standards of research and operational excellence.

Dr. Raksha Sunhare’s combination of scientific rigor, strategic thinking, and innovative approach positions her as a pioneering leader in probiotics and biotechnology research.

Publications Top Noted📚

Assessing the probiotic potential and safety of newly isolated Bacillus coagulans VHBAX-04: in vitro and in silico evaluations

Authors: Sunhare, R.; Shyam Prasad, S.V.; Kodimule, S.; Prabu, R.

Journal: International Journal of Food Science and Technology

Year: 2024

Production, purification, and biochemical analysis of RNase-producing mutant strain of Streptomyces venezuelae

Authors: Sunhare, R.; Punniyamorthy, G.; Prabu, R.

Journal: Minerva Biotecnologica

Year: 2013