Prof Dr. Mahmoud Ahmed, Biomolecules, Best Researcher Award

Prof Dr. Mahmoud Ahmed, Biomolecules, Best Researcher Award

Prof Dr. Mahmoud Ahmed, King Saud bin Abdulaziz University for Health Sciences, Saudi Arabia

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🎓Academic Qualifications

Dr. Mahmoud Ahmed Mansour completed his PhD in Physiological Chemistry from Karolinska Institutet, Stockholm, Sweden, between 1990 and 1993. His thesis focused on leukotrienes and lipoxins, particularly investigating the role of Leukotrienes C4 and B4 in chronic myeloid leukemia. Prior to that, he earned his Master’s degree in Biochemistry from Al-Azhar University, Cairo-Egypt, where his research centered on the role of steroidal hormones in breast cancer (1987-1990). He also obtained a Diploma in Biochemical Analysis from Al-Azhar University (1985-1986), and graduated with a Bachelor of Pharmaceutical Sciences with Honors from the Faculty of Pharmacy, Al-Azhar University, in 1984.

👩‍🏫Academic Experience 

Dr. Mansour has extensive academic experience spanning several prestigious universities. Since 2012, he has served as a Professor of Pharmaceutical Sciences at the King Saud bin Abdulaziz University for Health Sciences (KSAU-HS). From 2006 to 2012, he was a Professor in the Pharmacology Department at King Saud University (KSU). Additionally, he held the position of Professor of Pharmacology at King Faisal University (2005-2006) and was an Associate Professor in Biochemistry at Al-Azhar University from 2002 to 2005. Earlier in his career, he served as an Assistant Professor in both King Saud University and Al-Azhar University, where he taught a variety of courses in biochemistry, pharmacology, and clinical chemistry.

🔬Research Interests

Dr. Mansour’s research has contributed significantly to several fields of biochemistry and pharmacology. His primary interests include:

Leukotrienes and Lipoxins: Investigating their synthesis, quantitation, and biological effects.

Oxidative Damage and Free Radicals: Studying their role in tissue injury, aging, and cancer prevention.

Tumor Markers: Researching biomarkers for the early diagnosis of cancer.

Molecular Biology: Focusing on genetic techniques and oncogenic transformations.

Chemical Toxicities: Exploring biochemical changes related to aging and disease.

🧪Instrumental Expertise

Throughout his career, Dr. Mansour has gained substantial expertise in various laboratory techniques and instrumentation. These include spectrophotometry, high-performance liquid chromatography (HPLC), flow cytometry, PCR, enzyme-linked immunosorbent assays (ELISA), and tissue culture. His work in animal experimentation covers fields such as induced liver damage, diabetes, hyperlipidemia, and tumors. He has also developed proficiency in ultracentrifugation, electrophoresis, and atomic absorption techniques.

🏅Honors and Awards

Dr. Mansour has been recognized with several honors and awards throughout his distinguished career. In 1983, he received a Travel Award to attend the International Pharmaceutical Students Federation Conference in Lausanne, Switzerland. In 1998, he was awarded the prestigious State Encouragement Award in Medical Sciences, recognizing his contributions to the field of biochemistry and pharmacology.

👨‍🏫Teaching Contributions

Dr. Mansour has been a dedicated educator for undergraduate and graduate students across multiple institutions. He has taught courses in Biochemistry, Pharmacology, Toxicology, Clinical Chemistry, and Pharmacogenomics. He has served on examination boards for undergraduates and postgraduates at various faculties of pharmacy in Egypt, and has contributed to curriculum development and student progress committees at KSAU-HS.

🖥️Computer Skills

Dr. Mansour is highly proficient in a range of computer applications, including MS Windows, Mac OSX, and various academic tools like MS Publisher, MS Office, and Adobe Acrobat Pro. He also possesses advanced knowledge of the internet and emerging technologies that are applicable to academia, such as the iPad and smart pens.

📝Publications Top Noted

A possible antineoplastic potential of selective, irreversible proteasome inhibitor, carfilzomib on chemically induced hepatocarcinogenesis in rats

Authors: Mansour, M.A., Aljoufi, M.A., Al-Hosaini, K., Al-Rikabi, A.C., Nagi, M.N.
Journal: Journal of Biochemical and Molecular Toxicology
Year: 2014

Possible role of selective, irreversible, proteasome inhibitor (carfilzomib) in the treatment of rat hepatocellular carcinoma

Authors: Mansour, M.A., Aljoufi, M.A., Al-Hosaini, K., Al-Rikabi, A.C., Nagi, M.N.
Journal: Chemico-Biological Interactions
Year: 2014

Evaluation of oxidative stress and antioxidant status in diabetic and hypertensive women during labor

Authors: Al-Shebly, M.M., Mansour, M.A.
Journal: Oxidative Medicine and Cellular Longevity
Year: 2012

Comparison of angiotensin converting enzyme inhibitors and angiotensin II type 1 receptor blockade for the prevention of premalignant changes in the liver

Authors: Mansour, M.A., Al-Ismaeel, H., Al-Rikabi, A.C., Al-Shabanah, O.A.
Journal: Life Sciences
Year: 2011

Metformin attenuates streptozotocin-induced diabetic nephropathy in rats through modulation of oxidative stress genes expression

Authors: Alhaider, A.A., Korashy, H.M., Sayed-Ahmed, M.M., Kfoury, H., Mansour, M.A.
Journal: Chemico-Biological Interactions
Year: 2011

Ginger ingredients inhibit the development of diethylnitrosoamine induced premalignant phenotype in rat chemical hepatocarcinogenesis model

Authors: Mansour, M.A., Bekheet, S.A., Al-Rejaie, S.S., Al-Rikabi, A.C., Abdo, A.A.
Journal: BioFactors
Year: 2010

Dr. Sabine Pellett, Biomolecules, Best Researcher Award

Dr. Sabine Pellett, Biomolecules, Best Researcher Award

Doctorate at University of Wisconsin-Madison, United States

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🎓Educational Background

B.S. in Biology
University of Heidelberg, Heidelberg, Germany (1995)

M.A. in Biology
Portland State University, Portland, OR (1997)

Ph.D. in Environmental & Molecular Toxicology
University of Wisconsin-Madison (2004)

Postdoctoral Fellowship in Food Microbiology & Toxicology
University of Wisconsin-Madison (2005-2007)

💼Professional Experience

Research Associate Professor
Department of Bacteriology, UW-Madison (July 2023 – present)

Limited PI Status
Department of Bacteriology, UW-Madison
(2013, 2015, 2018, and renewed in 2021)

Instructional Staff
Bacteriology, UW-Madison (Spring 2020)

Senior Scientist
Bacteriology, UW-Madison (2016-2023)

Associate Scientist
Bacteriology, UW-Madison (2012-2016)

Researcher
Bacteriology, UW-Madison (2010-2012)

Associate Researcher
Bacteriology, UW-Madison (2007-2010)

Research Associate
Food Microbiology and Toxicology, UW-Madison (2005-2007)

Research Assistant
Environmental & Molecular Toxicology, UW-Madison (1998-2004)

Teaching Assistant
Environmental & Molecular Toxicology, UW-Madison (2001)

🔬Research Interests

Botulinum Neurotoxin research and its applications in treating diseases.

Development of vaccines against botulism.

Investigation of the mechanisms of bacterial toxin action.

Food safety, specifically detection and analysis of foodborne pathogens.

🏆Grants and Awards:

Past

NIH Grants:
Participated in and co-managed multiple NIH-funded projects focused on botulinum neurotoxin research, including studies on novel therapeutic approaches, vaccine development, and toxin characterization.

Agilent Microarray Award (2013):
Received a small grant to test Agilent’s microarray platform.

USDA Agricultural Research Service Grants:
Co-investigator on projects related to the development of detection technologies and therapeutics for botulinum neurotoxins.

Current

NIH R01AI118389 (2020-2025):
Vaccines Against Botulism (co-PI)

NIH R01AI139306-01A1 (2019-2024):
Characteristics of Botulinum Neurotoxins that Determine Potency (PI)

USDA Agricultural Research Service (2020-2025):
Development of Detection Technologies and Therapeutics for Botulinum Neurotoxins (co-PI)

WEDC-SEED (D2P):
Optimization of botulinum neurotoxin production for pharmaceutical use (PI)

📝Publication Top Noted

Botulinum neurotoxin X lacks potency in mice and in human neurons

Authors: Gregg, B.M., Matsumura, T., Wentz, T.G., Fujinaga, Y., Pellett, S.

Journal: mBio

Year: 2024

Recent Developments in Vaccine Design: From Live Vaccines to Recombinant Toxin Vaccines

Authors: Gupta, S., Pellett, S.

Journal: Toxins

Year: 2023

Special Issue: Gram-Positive Bacterial Toxins

Authors: Sharma, S., Pellett, S., Morse, S.A.

Journal: Microorganisms

Year: 2023

Botulinum Neurotoxin A4 Has a 1000-Fold Reduced Potency Due to Three Single Amino Acid Alterations in the Protein Receptor Binding Domain

Authors: Tepp, W.H., Bradshaw, M., Gardner, A.P., Barbieri, J.T., Pellett, S.

Journal: International Journal of Molecular Sciences

Year: 2023

Transformation of a Metal Chelate into a “Catch and Anchor” Inhibitor of Botulinum A Protease

Authors: Lin, L., Patel, E.N., Nielsen, A.L., Pellett, S., Janda, K.

Journal: International Journal of Molecular Sciences

Year: 2023

How Botulinum Neurotoxin Light Chain A1 Maintains Stable Association with the Intracellular Neuronal Plasma Membrane

Authors: Gardner, A.P., Barbieri, J.T., Pellett, S.

Journal: Toxins

Year: 2022

 

Dr. Ashok Kumar Janakiraman, Biomolecules, Innovation Award

Dr. Ashok Kumar Janakiraman, Biomolecules, Innovation Award

Doctorate at UCSI University, Malaysia

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Education 🎓

  • Ph.D. in Pharmacy (Pharmaceutics), PRIST University, Thanjavur, 2010-2013
    Research Topic: Design and Evaluation of Sustained Release Formulations of Nano Carvedilol
  • M. Pharm in Pharmaceutics, SASTRA University, Thanjavur, 2006-2008
    Research Topic: Formulation and Evaluation of Olmesartan Medoxomil and Hydrochlorothiazide combination as tablets
  • B. Pharm in Pharmaceutical Sciences, The TN Dr. M.G.R Medical University, Tamil Nadu, 2001-2004
    Research Topic: Standardization of Essential oils of Genus “Jasminum”
  • D. Pharm in Pharmacy, Directorate of Medical Education, Madras, 1997-1999
  • PGDTT in Teaching and Learning, UCSI University, Malaysia, 2017-2019

Professional Experience 💼

  • Assistant Professor, Faculty of Pharmaceutical Sciences, UCSI University, Kuala Lumpur, Malaysia (2017-Present)
  • Lecturer, Faculty of Pharmaceutical Sciences, UCSI University, Kuala Lumpur, Malaysia (2015-2016)
  • Research Associate, Formulation Research & Development (Topical products), Apex Laboratories Private Limited, Chennai, India (2013-2015)
  • Research Scholar and Assistant Professor, Faculty of Pharmacy, PRIST University, Thanjavur (2008-2012)

Research Interests 🔬

  • Pharmaceutical Nanotechnology: Solubility enhancement of poorly water-soluble drugs, Green synthesized nanoparticles
  • Topical Products: Cream, Serum, Ointment, Gel
  • Oral Dispersible Tablets: Chocolate-based drug delivery
  • Polyherbal Formulation
  • Sustained Release Tablets
  • Microspheres
  • Transdermal Patches
  • In Situ Gel Eye Drops

Achievements 🏆

  • Published 60 papers in international and national journals
  • Secured RM 500K in research grants
  • Received 12 recognitions and awards
  • Developed new programs: 1 PG, 1 UG, 2 Diplomas
  • Filed 4 patents and 1 trademark
  • Published 4 book chapters
  • Guided 15 master's student projects
  • Presented papers at 30 international and national conferences
  • Served as a thesis examiner for several prestigious universities in India
  • Editorial board member and reviewer for multiple scientific journals

Patents and Trademark 📜

  • Machines for development and production of solid pharmaceutical products (India)
  • Fabrication of cocoa butter fast melting tablets by simple freezing method (India)
  • A system for administering nanocarriers for the treatment of chronic diseases (Germany)
  • Method for preparation and enhancing dissolubility by the liquisolid compaction techniques (India)
  • Trademark: CocoameltsTabs™

Program Development 📚

  • Head of Programme: Diploma in Cosmetic Science (MQA/PA15586), UCSI University
  • Bachelor of Formulation Science (Honors) (MQA/PA 13963), UCSI University
  • Involved in the review and revamp of the Master of Pharmaceutical Technology program.

Notable Publication📰

  • Paper Title: An Overview of Various Approaches for Brain Targeted Drug Delivery System
    • Authors: Kamlesh Patel, Tejal Gandhi, Dinesh Kumar Chellappan, and Dhruv Patel
    • Journal: Current Drug Delivery
    • Year: 2020
  • Paper Title: Biodegradable polymeric insulin microneedles–a design and materials perspective review
    • Authors: Abhijeet D. Bansode, Neeraj Upmanyu, and Dinesh Kumar Chellappan
    • Journal: Journal of Drug Delivery Science and Technology
    • Year: 2020
  • Paper Title: An Expedition Towards Formulating Natural Face Serum with Garcinia mangostana (Mangosteen)
    • Authors: Rosniza Razali, Ain Uzura Zawawi, and Mohd Cairul Iqbal Mohd Amin
    • Journal: Journal of Applied Pharmaceutical Science
    • Year: 2020
  • Paper Title: Formulation and Development of Poly-Herbal Anti-ageing Cream
    • Authors: Udhaya Lavinya Baskaran, Aishwarya Senthil Kumar, and Sudhakar Bhoopathy
    • Journal: Asian Journal of Pharmaceutical Research and Development
    • Year: 2020
  • Paper Title: Compounding and Characterization of Oral Disintegrating Films Containing Memantine Hydrochloride for Geriatrics
    • Authors: Sameer Basavraj Banagar, Bhagyashree Shahaji Jadhav, and Dinesh Kumar Chellappan
    • Journal: Journal of Drug Delivery Science and Technology
    • Year: 2020