Doctorate at College of life science, Hebei normal university | China
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🎓 Educational Background
Dr. Jingtian He has a robust academic foundation that underpins her expertise in biochemistry and molecular biology. She earned her Bachelor of Science (B.S.) in Chemistry from Hebei University, Baoding, China in July 1990. Her pursuit of advanced knowledge led her to Nankai University, Tianjin, China, where she completed her Master of Science (M.S.) in Inorganic Chemistry in June 1996. Dr. He culminated her academic journey with a Ph.D. in Biochemistry and Molecular Biology from the prestigious School of Basic Medical Sciences, Fudan University, Shanghai, China, in June 2005.
🏢 Professional Role and Expertise
Currently, Dr. Jingtian He serves as an Associate Professor in the Department of Biochemistry and Molecular Biology at the College of Life Science, Hebei Normal University, located in Shijiazhuang City, Hebei Province, China. She is a distinguished academic and researcher known for her contributions to drug delivery systems and her innovative work in micro- and nano-particle formulations.
💡 Research Focus
Dr. He’s research is centered on the development of polymeric particles for sustained and mucosal drug delivery systems, contributing significantly to advancements in pharmaceutical science. Her work has provided a deeper understanding of microsphere formulations for a variety of drugs, including erythropoietin, hepatitis B surface antigen, staphylokinase mutant, triptorelin, and non-T cell binding peptides.
One of her groundbreaking discoveries demonstrated that chitosan can enhance the transepithelial transport of both peptides and microparticles, offering new possibilities for improving drug delivery and absorption. Additionally, her research highlighted that the surface modification of PLGA micro- and nano-particles with polysaccharides serves as a promising approach for the mucosal delivery of antigens, paving the way for innovative solutions in vaccine and therapeutic delivery systems.
Publications Top Noted📚
Enhanced phagocytosis and endosomal escape of glucan-modified microparticles in antigen-presenting cells
Authors: Kang, T.; Zhang, R.; Hou, S.; He, J.
Journal: Journal of Drug Delivery Science and Technology
Year: 2024
Adjuvant effects of chimeric flagellin and chitosan/tripolyphosphate (CS/TPP) nanogel encapsulation on immune response induced by nasal vaccination of Helicobacter pylori adhesin
Authors: Zhai, X.; Yan, X.; Meng, Q.; He, J.; Wang, G.
Journal: Acta Microbiologica Sinica
Year: 2021
Chitosan-based thermosensitive hydrogel for nasal delivery of exenatide: Effect of magnesium chloride
Authors: Li, Y.; He, J.; Lyu, X.; Wang, G.; Zhao, B.
Journal: International Journal of Pharmaceutics
Year: 2018
Co-delivery of polyinosinic:polycytidylic acid and flagellin by poly(lactic-co-glycolic acid) MPs synergistically enhances immune response elicited by intranasally delivered hepatitis B surface antigen
Authors: Dai, X.; He, J.; Zhang, R.; Xiong, F.; Zhao, B.
Journal: International Journal of Nanomedicine
Year: 2017
Surface-functionalized, pH-responsive poly(lactic-co-glycolic acid)-based microparticles for intranasal vaccine delivery: Effect of surface modification with chitosan and mannan
Authors: Li, Z.; Xiong, F.; He, J.; Dai, X.; Wang, G.
Journal: European Journal of Pharmaceutics and Biopharmaceutics
Year: 2016