Dr. Hewang Lee, Medicinal Chemistry, Outstanding Scientist Award

Doctorate at George Washington University, United States

Professional Profile

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🌟 Summary

• Dr. Lihua is a seasoned Research Scientist at George Washington University, specializing in the metabolic mechanisms of hypertension and chronic kidney diseases. With a robust background spanning prestigious institutions like NIH and Max-Planck Institute, Dr. Lihua has made significant contributions to understanding renal regulation, energy metabolism, and neuropeptide functions.

🎓 Education

• Ph.D. in Medical Science, Beijing Medical University, 1997
• M.S. in Medical Science, Shanghai Medical University, 1993
• M.D. in Clinical Medicine, Bengbu Medical College, 1990

👩‍🔬 Professional Experience

• Research Scientist, George Washington University, 2020 – Present
  • Leading projects on NPFF, SNX19, PRDX4, and autophagy in hypertension.
• Statistical Analyst and Programmer, Rang Technologies, 2019 – 2020
  • Clinical research in oncology, cardiovascular, and renal diseases.
• Researcher, Dalian Medical University, 2015 – 2018
  • Investigated metabolic mechanisms in chronic kidney diseases.
• Postdoc Scientist, University of Maryland and Children National Medical Center, 2009 – 2015
  • Explored sodium reabsorption regulation and GPCR trafficking in hypertension.

🔍 Research Interests

• Hypertension mechanisms
• Neuropeptides and dopamine interactions
• Autophagy and renal diseases

Publication Top Noted📝

• Article: Poly-(ADP-ribose) polymerases inhibition by olaparib attenuates activities of the NLRP3 inflammasome and of NF-κB in THP-1 monocytes

  • Authors: Mustafa, K., Han, Y., He, D., Lee, H., Qu, P.
  • Journal: PLoS ONE
  • Volume: 19
  • Issue: 2 (February)
  • Pages: e0295837
  • Year: 2024

• Article: Peroxiredoxin-4 and Dopamine D5 Receptor Interact to Reduce Oxidative Stress and Inflammation in the Kidney

  • Authors: Amatya, B., Yang, S., Yu, P., Lee, H., Jose, P.A.
  • Journal: Antioxidants and Redox Signaling
  • Volume: 38
  • Issue: 16
  • Pages: 1150–1166
  • Year: 2023

• Article: RNA-Seq analysis of obese Pdha1fl/flLyz2-Cre mice induced by a high-fat diet

  • Authors: Geng, Z., Yuan, Y., He, D., Tang, Z., Qu, P.
  • Journal: Experimental Animals
  • Volume: 72
  • Issue: 1
  • Pages: 112–122
  • Year: 2023

• Article: The Correlation between Increased Expressions of NLRP3 Inflammasome Components in Peripheral Blood Mono-Nuclear Cells and Plaque Vulnerability in Human Carotid Atherosclerosis

  • Authors: Xie, W., Shi, X., Lee, H., Niu, N., Qu, P.
  • Journal: Iranian Journal of Public Health
  • Volume: 52
  • Issue: 1
  • Pages: 147–158
  • Year: 2023

• Article: HIV-1 Vpr suppresses expression of the thiazide-sensitive sodium chloride cotransporter in the distal convoluted tubule

  • Authors: Shrivastav, S., Lee, H., Okamoto, K., Kino, T., Kopp, J.B.
  • Journal: PLoS ONE
  • Volume: 17
  • Issue: 9 (September)
  • Pages: e0273313
  • Year: 2022