Professor at Chongqing Medical University, China
Professional Profiles
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🎓Academic and Professional Background
Chungang LIU is currently an Investigator at Chongqing Medical University. He earned his Ph.D. from the School of Medicine at Zhejiang University, focusing on cancer stem cells and cell division. His postdoctoral training was at the IMCB of A*STAR, where he identified and characterized several proteins involved in protein homeostasis through ubiquitination modification, including the SOX9 and YTHDF1 complexes. In 2019, he became an independent investigator at the Third Military Medical University and was appointed A*STAR IMCB Research Fellow. In January 2021, he moved his laboratory to the Second Affiliated Hospital, Chongqing Medical University.
🔗Professional Memberships
Prof. Chungang Liu is a distinguished member of the Chinese Society of Cell Biology. His active involvement in this professional community reflects his dedication to advancing research in the field of cell biology. His contributions to understanding the molecular mechanisms of protein post-translational modifications and cancer research align with the mission of the Society to promote scientific discovery and innovation. Prof. Liu’s expertise in epigenetics and cancer stem cells continues to foster valuable exchanges within this prominent scientific network.
🔬Research Areas
Chungang LIU’s research focuses on Protein Post-Translational Modification and Functional Regulation. His team uses integrative proteomics to uncover how epigenetic modifying enzymes drive cancer treatment tolerance. They also explore how inhibitors of these enzymes can enhance the effectiveness of Sorafenib or immune checkpoint blockade (ICB) treatment. Additionally, Chungang’s lab has revealed the molecular mechanisms of ubiquitination modification regulating target protein homeostasis and inhibiting the symmetric division of cancer stem cells.
Publications Top Noted📝
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GASC1 promotes hepatocellular carcinoma progression by inhibiting the degradation of ROCK2
- Authors: Na Shao, Jiamin Cheng, Hong Huang, Feng Xu, Chungang Liu
- Journal: Cell Death and Disease
- Year: 2021
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KEAP1 Mutations Drive Tumorigenesis by Suppressing SOX9 Ubiquitination and Degradation
- Authors: Na Shao, Hong Huang, Muhammad Idris, Shiwu Dong, Chungang Liu
- Journal: Advanced Science
- Year: 2020