Prof. Bali Pulendran | Applied Chemistry | Best Researcher Award

Professor at Stanford University, United States

Professional Profiles

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๐ŸŽ“ Educational Background

Bali Pulendran laid the foundation for his illustrious career at Queensโ€™ College, University of Cambridge, earning a BA (Honors) (1985โ€“1988) under the mentorship of Professor Ron Laskey from the Department of Zoology. Prior to this, he excelled in his GCE Oxford & Cambridge “A” Levels at Reigate Grammar School, Surrey, England (1982โ€“1984).

๐Ÿ”ฌ Postgraduate Training

Dr. Pulendran advanced his expertise as a Postdoctoral Fellow at Immunex Corporation, Seattle (1995โ€“1998), where he collaborated with Drs. Charles Maliszewski and Eugene Maraskovsky. He completed his Ph.D. at The Walter & Eliza Hall Institute, University of Melbourne (1991โ€“1995), under the guidance of the esteemed Prof. Sir Gustav Nossal, contributing to groundbreaking immunological research.

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๐Ÿ›๏ธ Previous Academic and Professional Appointments

Dr. Bali Pulendran has held numerous esteemed positions throughout his illustrious academic career. From 2008 to 2017, he served as the Director of the Innate Immunity Program and held the prestigious title of Charles Howard Candler Professor in Pathology at Emory University, where he advanced groundbreaking research in immunology and vaccinology. Since 2005, he has been a Professor and Researcher at the Emory Vaccine Center, contributing significantly to the study of immune responses and vaccine development. Prior to this, he served as an Associate Professor from 2002 to 2004 and an Assistant Professor from 1999 to 2001 at the Baylor Institute for Immunology Research in Dallas, Texas. These roles underscore Dr. Pulendran’s profound contributions to the fields of innate immunity, vaccine science, and immunological research, establishing him as a leader in his domain.

๐Ÿงฌ Research Interests

Dr. Pulendran’s research lies at the interface of immunology, vaccinology, virology, and systems biology, focusing on how the innate immune system senses pathogens and modulates the adaptive immune response to achieve protective immunity. His lab has pioneered multi-omics approaches to analyze immune responses to vaccination and infection in humans, uncovering molecular signatures that predict vaccine immunity.

Key discoveries include:

The influence of the microbiome on vaccine efficacy.

Roles of amino acid sensing and cholesterol metabolism in regulating dendritic cells and adaptive immunity.

Identifying pathways and receptors crucial for durable antibody responses and long-lived bone marrow plasma cells.

This knowledge has been instrumental in the design and testing of novel vaccine adjuvants, including vaccines against COVID-19.

Publications Top Noted๐Ÿ“šย 

“Induction of Tier 2 HIV-Neutralizing IgA Antibodies in Rhesus Macaques Vaccinated with BG505.664 SOSIP”

Authors: Smith, J.C., Arunachalam, P.S., Legere, T.H., Amara, R.R., Kozlowski, P.A.

Journal: Vaccines

Year: 2024

“IgM N-glycosylation correlates with COVID-19 severity and rate of complement deposition”

Authors: Haslund-Gourley, B.S., Woloszczuk, K., Hou, J., Sierra, B., Hughes, T.

Journal: Nature Communications

Year: 2024

“Acute and persistent responses after H5N1 vaccination in humans”

Authors: Apps, R., Biancotto, A., Candia, J., Schwartzberg, P.L., Tsang, J.S.

Journal: Cell Reports

Year: 2024

“Transforming vaccinology”

Authors: Rappuoli, R., Alter, G., Pulendran, B.

Journal: Cell

Year: 2024

“Elucidating allergic reaction mechanisms in response to SARS-CoV-2 mRNA vaccination in adults”

Authors: Shah, M.M., Layhadi, J.A., Hourcade, D.E., Pham, C.T.N., Nadeau, K.C.

Journal: Allergy: European Journal of Allergy and Clinical Immunology

Year: 2024

Prof. Bali Pulendran | Applied Chemistry | Best Researcher Award

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