Prof. Mahmoud Abd-Elkareem – Medicinal Chemistry – Best Researcher Award

Assiut University, Egypt

Author Profile

🎓Academic and Professional Background

Mahmoud Abd-Elkareem Mahmoud is a Professor in the Department of Cell and Tissues at the Faculty of Veterinary Medicine, Assiut University. He has established himself as a distinguished researcher in the field of reproductive biology and histopathology. Over the years, he has published numerous high-impact articles in international journals, contributing significantly to the scientific community. In addition to his research, he serves as an editor and reviewer for various renowned international journals, ensuring the dissemination of high-quality scientific knowledge.

🔬Research Interests

His research expertise spans multiple areas within biomedical sciences. His primary interests include reproductive biology, particularly focusing on the development of the ovary and embryology. He has also extensively studied stem cells, applying advanced techniques such as electron microscopy, histopathology, and immunohistochemistry. His work further extends into cytopathology and frozen section analysis, offering insights into cellular structures and disease pathology.

📑Ongoing Research & Projects

Currently, Mahmoud Abd-Elkareem is leading an innovative research project on the effects of Miswak aqueous extract on reproductive performance. His study explores the therapeutic potential of Salvadora persica (Miswak), particularly in adult rats exposed to excess testosterone, with a special focus on its protective effects on the brain and testis. His research aims to uncover natural remedies for reproductive and neurological health challenges, advancing the field of alternative medicine and toxicology.

🏅Professional Memberships

Mahmoud Abd-Elkareem actively participates in several professional organizations, contributing to quality assurance and scientific advancements in veterinary medicine. He is a member of the Quality Assurance and Accreditation Project and the Quality Assurance Unit at the Faculty of Veterinary Medicine, Assiut University. Additionally, he is affiliated with the Egyptian Society of Histology & Cytology, further strengthening his engagement with the global scientific community.

🌍Impact and Contributions

With his extensive knowledge and commitment to scientific research, Mahmoud Abd-Elkareem continues to make remarkable contributions to the fields of histopathology, reproductive biology, and cytopathology. His dedication to academic excellence and innovative research has positioned him as a leading figure in veterinary and biomedical sciences.

Notable Publications📝

📝Antioxidant and cytoprotective effects of Nigella sativa L. seeds on the testis of monosodium glutamate challenged rats

Authors: Abd-Elkareem, M.; Abd El-Rahman, M.A.M.; Khalil, N.S.A.; Amer, A.S.
Journal: Scientific Reports
Year: 2021

📝Broiler welfare is preserved by long-term low-dose oral exposure to zinc oxide nanoparticles: preliminary study

Authors: Mahmoud, M.A.M.; Yahia, D.; Abdel-Magiud, D.S.; Darwish, M.H.A.; Abd-Elkareem, M.; Mahmoud, U.T.
Journal: Nanotoxicology
Year: 2021

📝Prebiotics reduce feather pecking behavior, and improve trace element profile and redox balance in Mule ducks

Authors: Mahmoud, U.T.; Mahmoud, M.A.M.; Abd-Elkareem, M.; Ahmed, F.A.M.; Khalil, N.S.A.
Journal: Journal of Veterinary Behavior
Year: 2021

📝Cytoprotective effect of Nigella sativa seed on 4-nonylphenol-induced renal damage in the African catfish (Clarias gariepinus)

Authors: Abd-Elkareem, M.; Abou Khalil, N.S.; Sayed, A.E.-D.H.
Journal: Chemosphere
Year: 2020

📝High-Payload chitosan microparticles for the colonic delivery of quercetin: Development and in-vivo evaluation in a rabbit colitis model

Authors: Helmy, A.M.; Elsabahy, M.; Abd-Elkareem, M.; Ibrahim, E.A.; Soliman, G.M.
Journal: Journal of Drug Delivery Science and Technology
Year: 2020

Dr. Aloïse Mabondzo | drug design | Best Researcher Award

Doctorate at CEA, France

Professional Profiles

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🎓 Educational Background

Dr. Aloïse Mabondzo, has a distinguished academic foundation. He earned his Master’s degree in Molecular and Cellular Biology from the University of Strasbourg, France (1986-1989). Driven by a passion for cutting-edge research, he pursued a PhD in Virology and Immunology at the prestigious Pierre and Marie Curie University, France (1989-1993). His doctoral work focused on Active Immunotherapy using bispecific antibodies against HIV, a testament to his early commitment to tackling global health challenges.

🧪 Professional Positions

Dr. Mabondzo’s illustrious career began with a Post-doctoral Research Fellowship (1993-1997) at the CEA Neurovirology Department, where he made significant contributions to the field of neurovirology. In 1998, he joined the CEA Medicine and Healthcare Technologies Department, where he has served as Research Director and Head of the Neurovascular Unit Research and Therapeutic Innovation Laboratory. His leadership in these roles has driven breakthroughs in neurovascular research. Since 2019, Dr. Mabondzo has also been the Co-founder and Research Director of Ceres Brain Therapeutics, a startup dedicated to pioneering therapeutic innovations.

👩‍🏫 Mentoring and Supervision

Dr. Mabondzo has a proven track record as a mentor and supervisor. Over his career, he has supervised 16 PhD candidates (10 past, 6 current), 7 Postdoctoral Fellows (4 past, 3 current), and several other researchers, including 2 Research Assistants, 2 Engineers, and 2 Technicians. His mentorship has nurtured the next generation of scientists, fostering innovation and collaboration.

Publications Top Noted📄

Dodecyl creatine ester therapy: from promise to reality

Authors: Mabondzo, A.; van de Kamp, J.; Mercimek-Andrews, S.

Journal: Cellular and Molecular Life Sciences

Year: 2024

A Fab of trastuzumab to treat HER2 overexpressing breast cancer brain metastases

Authors: Angeli, E.; Paris, J.; Le Tilly, O.; Paintaud, G.; Bousquet, G.

Journal: Experimental Hematology and Oncology

Year: 2024

Impaired brain glucose metabolism as a biomarker for evaluation of dodecyl creatine ester in creatine transporter deficiency: Insights from patient brain-derived organoids and in vivo [18F]FDG PET imaging in a mouse model

Authors: Disdier, C.; Soyer, A.; Broca-Brisson, L.; Tournier, N.; Mabondzo, A.

Journal: Neurobiology of Disease

Year: 2024

Targeting the Multiple Complex Processes of Hypoxia-Ischemia to Achieve Neuroprotection

Authors: Maïza, A.; Hamoudi, R.; Mabondzo, A.

Journal: International Journal of Molecular Sciences

Year: 2024

Epigenetic alterations in creatine transporter deficiency: a new marker for dodecyl creatine ester therapeutic efficacy monitoring

Authors: Broca-Brisson, L.; Disdier, C.; Harati, R.; Hamoudi, R.; Mabondzo, A.

Journal: Frontiers in Neuroscience

Year: 2024