Prof. Huping Xue | Microbiology | Best Researcher Award

Posted on by sciencefather

Prof. Huping Xue | Microbiology | Best Researcher Award

Professor at Northwest A&F University, China

Professional Profile

Scopus

🎓Early Education and Career Development 

Professor Xue Huping, PhD, earned his doctorate from Fudan University, one of China’s prestigious institutions. He continued his academic journey at McGill University between 2009 and 2011. In 2012, he joined the College of Animal Science and Technology at Northwest A&F University, where he now serves as a professor and PhD supervisor. Over the years, he has established himself as a significant figure in the academic community, with roles as an evaluating expert for the National Natural Science Foundation of China (NSFC) and communication review expert for dissertations of China’s Ministry of Education.

🔬💡Research Focus and Contributions 

Professor Xue’s research is dedicated to addressing the critical need for antibiotic substitutes in livestock breeding, particularly in response to China’s policy that prohibits the use of antibiotics in animal feed. His team is focused on antimicrobial peptides as a sustainable solution. The research primarily encompasses three key areas: First, they are mining new antimicrobial peptides from natural products and working to enhance their efficacy. Second, the team is investigating the mechanisms of antimicrobial peptides and their interactions with Staphylococcus aureus, a common and harmful bacteria in livestock. Lastly, they are working on developing high-expression systems using Escherichia coli, Bacillus subtilis, lactic acid bacteria, and Pichia pastoris to achieve large-scale production of antimicrobial peptides. To support this extensive research, Professor Xue’s lab is equipped with state-of-the-art instruments and equipment worth 2 million dollars, enabling in-depth studies in molecular biology, cell biology, and microbiology.

🏆Honors and Recognition 

Professor Xue has received numerous accolades for his groundbreaking work in antimicrobial research. Notably, he was the first winner of the Second Prize of Natural Science at the Shaanxi Province Science and Technology Award in 2019, for his work on the generation, transmission, and prevention of antibiotic resistance in bovine mastitis caused by Staphylococcus aureus. Furthermore, he serves as the Director of a university-level excellent study demonstration class, underscoring his leadership and commitment to education.

🏛️Professional Affiliations and Leadership 

Professor Xue is deeply embedded in various academic communities. He is a delegate to the national genetics congress, a standing member of the Shaanxi Pharmacological Society, and a member of the Chinese Society of Microbiology. His influence extends beyond research, contributing to the broader field of genetics and microbiology through his leadership and expert roles.

Publications Top Notedđź“ť

Unearthing New ccr Genes and Staphylococcal Cassette Chromosome Elements in Staphylococci Through Genome Mining

Authors: Huang, J., Xiao, J., Wang, X., Larsen, A.R., Xue, H.
Journal: Journal of Infectious Diseases
Year: 2024, 230(1), pp. 231–238

Novel cassette chromosome recombinases CcrA8B9 catalyse the excision and integration of the staphylococcal cassette chromosome mec element

Authors: Xiao, J., Huang, J., Xue, X., Zhao, X., Xue, H.
Journal: Journal of Antimicrobial Chemotherapy
Year: 2023, 78(2), pp. 440–444

Inducible Resistance to β-Lactams in Oxacillin-Susceptible mecA1-Positive Staphylococcus sciuri Isolated From Retail Pork

Authors: Cai, Y., Zheng, L., Lu, Y., Zhao, X., Xue, H.
Journal: Frontiers in Microbiology
Year: 2021, 12, 721426

Multiple tolerances and dye decolorization ability of a novel laccase identified from Staphylococcus haemolyticus

Authors: Li, X., Liu, D., Wu, Z., Zhao, X., Xue, H.
Journal: Journal of Microbiology and Biotechnology
Year: 2020, 30(4), pp. 615–621

Functional Analyses of Cassette Chromosome Recombinase C2 (CcrC2) and Its Use in Eliminating Methicillin Resistance by Combining CRISPR-Cas9

Authors: Wu, Z., Zhang, L., Qiao, D., Xue, H., Zhao, X.
Journal: ACS Synthetic Biology
Year: 2018, 7(11), pp. 2590–2599

Prof. Magda Gioia | microbiology | Best Researcher Award

Posted on by sciencefather

Prof. Magda Gioia | microbiology | Best Researcher Award

Professor at University of Rome Tor Vergata, Italy

Professional Profiles

Scopus

Orcid

🎓 Academic and Professional Background

Magda Gioia is an Associate Professor of Biochemistry at the University of Rome Tor Vergata, with a robust academic foundation in biochemistry and molecular biology. She earned her Ph.D. in Biochemistry and Molecular Biology from the University of Rome ‘Tor Vergata’ in 2005 and completed her Master’s in Biological Sciences at Roma Tre University in 2000. Her professional journey is marked by tenure-track and professorial roles, culminating in a Full Professor qualification in Italy in 2022.

Her research has significantly advanced biochemical and enzymatic processes, particularly through the DEGRADOMICs: CLIP-TAILs project, which introduced groundbreaking proteomic methods for identifying metalloprotease substrates. Currently, her work bridges structural biology and cellular biology, focusing on osteogenesis under pathological stimuli, bone resorption in microgravity, and mechanobiology in cancer cells.

🔬 Areas of Research

Magda’s research spans the dynamic fields of biochemistry, cell biochemistry, and mechanobiology. Her innovative contributions explore the biochemical mechanisms underlying cancer metastasis, osteogenesis, and microgravity-induced bone resorption.

🌍 Contributions to Research and Innovation

Motivated by the aggressive nature of osteosarcoma (OS) and the limitations of existing therapies, Magda’s research investigates how biophysical forces influence OS cell behavior. Through cutting-edge technologies like uniaxial stretch technology, advanced microscopy, and molecular assays, her studies have revealed:

Nuclear size alterations and changes in the nuclear-to-cytoplasmic ratio in OS cells under mechanical stimulation.

Activation of mechanosensitive (MS) channels, resulting in reactive oxygen species (ROS) accumulation, Src modulation, and histone H3 acetylation.

Impacts on cell motility, adhesion, and drug resistance, all critical factors in tumor progression.

đź“ś Professional Memberships

Magda is an active member of various prestigious professional organizations and societies dedicated to advancing biochemical research and innovation.

Publications Top Notedđź“ť

GsMTx-4 venom toxin antagonizes biophysical modulation of metastatic traits in human osteosarcoma cells

Authors: Buglione, A.; Alloisio, G.; Ciaccio, C.; Cricenti, A.; Gioia, M.

Journal: European Journal of Cell Biology

Year: 2025

Multi-Anticancer Activities of Phytoestrogens in Human Osteosarcoma

Authors: Cimmino, A.; Fasciglione, G.F.; Gioia, M.; Marini, S.; Ciaccio, C.

Journal: International Journal of Molecular Sciences

Year: 2023

Cyclic Stretch-Induced Mechanical Stress Applied at 1 Hz Frequency Can Alter the Metastatic Potential Properties of SAOS-2 Osteosarcoma Cells

Authors: Alloisio, G.; Rodriguez, D.B.; Luce, M.; Cricenti, A.; Gioia, M.

Journal: International Journal of Molecular Sciences

Year: 2023

Mechano-induced cell metabolism disrupts the oxidative stress homeostasis of SAOS-2 osteosarcoma cells

Authors: Fanelli, G.; Alloisio, G.; Lelli, V.; Rinalducci, S.; Gioia, M.

Journal: Frontiers in Molecular Biosciences

Year: 2023

Saliva Analysis of pH and Antioxidant Capacity in Adult Obstructive Sleep Apnea Patients

Authors: Venza, N.; Alloisio, G.; Gioia, M.; Danesi, C.; LaganĂ , G.

Journal: International Journal of Environmental Research and Public Health

Year: 2022