Prof. Wenhan Lin | Natural Product chemistry | Best Researcher Award

Professor at Ningbo Institute of Marine Medicine, Peking University | China

Professional Profile

🎓 Education and Academic Journey

Prof. Dr. Wenhan Lin has built an illustrious academic career in medicinal chemistry. He completed his undergraduate studies in Chemistry at the Department of Chemistry, Zhijiang Normal University (1978–1982). His graduate journey led him to the Shanghai Institute of Materia Medica, Chinese Academy of Sciences (1985–1989), where he earned his Master’s and Ph.D. degrees.
He further enhanced his expertise during a postdoctoral fellowship at the School of Pharmaceutical Sciences, Peking University (1990–1992). Recognized for his academic excellence, he joined the university as an Associate Professor of Medicinal Chemistry (1992–1996) and has been serving as a Professor in the State Key Laboratory of Natural and Biomimetic Drugs since 1996.

🌍 International Experience

Dr. Lin’s career has been enriched by various international scholarly visits. He worked as a visiting scholar at the Federal University of Rio de Janeiro, Brazil (1993–1994), the Faculty of Pharmaceutical Sciences, Toho University, Japan (1995–1996), and the University of Düsseldorf, Germany (1999–2000) under a prestigious DAAD Special Program Award.

🔬 Research Focus

Prof. Lin’s research primarily explores bioactive metabolites derived from marine organisms such as sponges, corals, and marine mangrove plants. His work also delves into the microorganisms associated with these ecosystems, aiming to uncover novel natural products with therapeutic potential.
His investigations include:

Isolation and structural elucidation of novel natural compounds.

Bioassay studies to evaluate the bioactivity of these compounds.

Structural modification of bioactive molecules for new drug development.

Studying the interactions between drugs and target proteins.

Publications Top Noted📝

Praelolide alleviates collagen-induced arthritis through increasing catalase activity and activating Nrf2 pathway

Authors: Qi, X., Meng, J., Li, C., Huang, J., Lin, W.

Journal: Phytomedicine

Year: 2024

Target Discovery of Dhilirane-Type Meroterpenoids by Biosynthesis Guidance and Tailoring Enzyme Catalysis

Authors: Sun, Z., Wu, M., Zhong, B., Lin, W., Fan, A.

Journal: Journal of the American Chemical Society

Year: 2024

Targeting bacterial phospholipids and their synthesis pathways for antibiotic discovery

Authors: Song, M., Chen, S., Lin, W., Zhu, K.

Journal: Progress in Lipid Research

Year: 2024

Three-dimensional structural alignment based discovery and molecular basis of AtoB, catalyzing linear tetracyclic formation

Authors: Ma, K., Liu, J., Huang, Z., Fan, A., Lin, W.

Journal: Chemical Science

Year: 2024

New Meroterpenes from South China Sea Soft Coral Litophyton brassicum

Authors: Chen, X., Zhang, J., Yang, J., Yan, X., He, S.

Journal: Marine Drugs

Year: 2024

Assoc Prof Dr. kasimujiang aximujiang, Natural Products Chemistry, Best Researcher Award

Assoc Prof Dr. kasimujiang aximujiang, xin jiang medical university, China

Professional Profiles

Scopus

🎓 Academic and Professional Background

With over ten years of research experience in intestinal diseases, I focus on the efficacy and mechanisms of herbal medicine and probiotics in their treatment. I have developed an innovative approach that combines probiotics with herbal medicine to effectively regulate the body and treat ulcerative colitis (UC). My research spans multiple dimensions, including metabolism, immunity, and gut microbiota, to study the pathogenesis and intervention mechanisms of UC. As a mentor, I supervise both master’s and undergraduate students, helping them explore the relationship between gut nerves and immunity to provide scientific evidence for UC treatment.

🔬 Research and Innovations

National Natural Science Foundation of China, Regional Science Fund Project

Focused on ulcerative colitis, this project explored the molecular mechanisms of herbal medicine and probiotics in treating UC.

Natural Science Foundation of the Autonomous Region

An in-depth investigation into the pathways and processes involved in the effectiveness of traditional Chinese medicine for UC treatment.

Youth Natural Science Foundation Project

A study focused on the role of gut microbiota and immune response in addressing intestinal diseases, particularly ulcerative colitis.

Innovation and Entrepreneurship Training Program of Xinjiang Medical University

Explored how the combination of herbal remedies and probiotics can offer a breakthrough in UC treatment, focusing on the interaction between gut microbiota and immune function.

🧪 Areas of Research

I concentrate on the pathogenesis of metabolic diseases and how traditional Chinese medicine can offer interventions. My research is based on the interaction between the gut microbiota and host metabolism, specifically focusing on ulcerative colitis. I aim to provide innovative treatments through the combination of probiotics and herbal medicine, and I supervise students as they explore the relationship between gut nerves and immunity to uncover new methods for treating UC.

🎖️ Contributions

My research contributes to a deeper understanding of ulcerative colitis by investigating its pathogenesis through the lenses of metabolism, immunity, and gut microbiota. By combining probiotics with herbal medicine, I offer an innovative and effective treatment approach. Additionally, I support the academic growth of students, guiding them in researching the relationship between gut health and immune system regulation, with the goal of advancing treatments for intestinal diseases.

Publications Top Noted📄

Effect of huankuile on colon injury in rats with ulcerative colitis by reducing TNF-α and MMP9

Authors: Wushouer, X., Aximujiang, K., Kadeer, N., Zhong, L., Yunusi, K.

Journal: European Journal of Medical Research

Year: 2024

L.acidophilus HSCC LA042 and HKL suspension ameliorate DSS-induced ulcerative colitis in mice by improving the intestinal barrier inhibiting the NLRP3 inflammasome and pathogenic bacteria

Authors: Zhu, J., Wang, H., Aisikaer, M., Yunusi, K., Aximujiang, K.

Journal: Heliyon

Year: 2024

Lactobacillus acidophilus and HKL Suspension Alleviates Ulcerative Colitis in Rats by Regulating Gut Microbiota, Suppressing TLR9, and Promoting Metabolism

Authors: Aximujiang, K., Kaheman, K., Wushouer, X., Ahemaiti, A., Yunusi, K.

Journal: Frontiers in Pharmacology

Year: 2022

The Antitumor Effect and Mechanism of Total Flavonoids From Coreopsis Tinctoria Nutt (Snow Chrysanthemum) on Lung Cancer Using Network Pharmacology and Molecular Docking

Authors: Wufuer, Y., Yang, X., Guo, L., Yunusi, K., Wu, G.

Journal: Frontiers in Pharmacology

Year: 2022

Correction to: Gut microbiota influence tumor development and Alter interactions with the human immune system

Authors: Ge, Y., Wang, X., Guo, Y., Yan, J., Wu, M.

Journal: Journal of Experimental & Clinical Cancer Research

Year: 2021